Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity connected to bortezomib, a proteasome inhibitor Employed in the treatment of many myeloma. Its synthesis or review is crucial for ensuring the purity and security with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor inside the synthesis of abiraterone acetate, a drug used in the treatment of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-one): A key compound in the synthesis of imatinib, a drug that targets distinct sorts of most cancers, like chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers for instance breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are typically intermediates from the synthesis of gemcitabine, an anti-most cancers drug. Their research is crucial for optimizing the creation procedure and guaranteeing high purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is used to take care of breast cancer, and these intermediates are linked to its creation.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the therapy of breast cancer. Different intermediates help in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug successful in managing cancers for instance ovarian, breast, and lung cancer.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the therapy of colorectal most cancers and compact mobile lung cancer.
3-Amino-one-hydroxyadamantane (CAS 702-82-9): This compound is linked to the synthesis of Afatinib-1 adamantane derivatives, that have several applications, which CAS NO. 231278-20-9 include antiviral Homes.
Vildagliptin Intermediates: Employed in the production of vildagliptin, an oral drug for style 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved with the synthesis of various gluconic acid derivatives, that are used in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor from the synthesis of canagliflozin, a medication utilized to manage sort two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).